Endometrial carcinoma

1. Life time risk of developing endometrial carcinoma
a] <1%
b] 2-3%
c] 4-5%
d] 6%

2. In type 1 endometrial ca all are true except
a] 75-85%
b] older age
c] perimenopausal age group
d] mutations in PTEN tumor suppressor gene

3. In type 2 endometrial ca all are true except
a] older age
b] poorly differentiated
c] obese women
d] mutations in p53 tumor suppressor gene

4. All are risk factors for endometrial ca except
a] tamoxifen therapy
b] atypical endometrial hyperplasia
c] HNPCC syndrome
d] OCP's

5. Life time risk of endometrial ca in HNPCC syndrome is
a] 10%
b] 20-30%
c] 40-60%
d] 70-80%

6. Criteria for cytological atypia include all of the following except
a] decreased nuclear to cytoplasmic ratio
b] prominent nucleoli
c] irregularly clumped chromatin
d] b and c
e] all of the above

7. What percentage of atypical hyperplasia detected in endometrial biopsy will have an associated endometrial ca at hysterectomy
a] 10-15%
b] 25-40%
c] 50-60%
d] none

8. Screening test of choice for endometrial ca
a] pap smear
b] endometrial cytological assessment
c] ultrasound
d] none of above

9. Average age for endometrial ca
a] 40yrs
b] 50yrs
c] 60yrs
d] 70yrs

10. Most common presentation of endometrial ca
a] asymptomatic
b] vaginal bleeding
c] pain abdomen
d] mass per abdomen